Abstract Background Tandem mass spectrometry (MS MS) and simple fluorometric assays are currently used in newborn screening programs to detect inborn errors of metabolism (IEM).The aim of the study was to evaluate the clinical utility of exome sequencing as a second tier screening method to assist clinical diagnosis of the newborn.Methods A novel P
This study investigates present and future European heat wave magnitudes, represented by the Heat Wave Magnitude Index-daily (HWMId), for regional climate models (RCMs) and the driving global climate models (GCMs) over Europe.A subset of the large EURO-CORDEX ensemble is employed to study sources of uncertainties related to the choice of GCMs, RCMs
Abstract Ultrasound stimulation is a type of mechanical stress, and low-intensity pulsed ultrasound (LIPUS) devices have been used clinically to promote fracture healing.However, it remains unclear which skeletal cells, in particular osteocytes or osteoblasts, primarily respond to LIPUS stimulation and how they contribute to fracture healing.To exa
Background: Pneumoconiosis defined as the accumulation of dust in the lungs and causes tissue reactions to mineral materials from various industries that affect the respiratory system.Among the causes of pneumoconiosis are silica dust (silicosis) and iron dust (ciderosis).Pneumoconiosis provides a pathological reaction in lung tissue due to inhaled
By studying the clutch of parallel hybrid electric vehicle,the state judgment model and working process model based on logic threshold control strategy are established.The operation control principle of clutch in parallel hybrid electric vehicle is analyzed and the control model is set up.The feasibility alphapro of the logic threshold control in t